产品编号：C380090

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	C380090
名称:	N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine
别名:	N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine
CAS号:	444731-75-3
分子式:	C₁₄H₁₄ClN₅
外观:	白色至Light Beige to Beige Solid
熔点:	174-176°C
分子量:	287.75
储存:	Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine is an impurity of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
参考文献	Mei, Y.C., et al.: Lett. Org. Chem., 9, 276 (2012); Li, Y., et al.: J. Pharma. Biomed. Anal., 52, 493 (2010); Harris, P.A., et al.: J. Med. Chem., 51, 4632 (2008);