产品编号：C379592

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C379592
名称:	1-(3-Chlorophenyl)piperazine-d8
别名:	1-(m-Chlorophenyl)piperazine-d8; 4-(3-Chlorophenyl)piperazine-d8;N-(3-Chlorophenyl)piperazine-d8; N-(m-Chlorophenyl)piperazine-d8; NSC 49307-d8; mCPP-d8;
CAS号:	1189923-43-0
参考CAS:	未标记: 6640-24-0
分子式:	C₁₀H₅D₈ClN₂
外观:	Cleat Colorless to Yellow Oil to Yellow Solid
熔点:	N/A
分子量:	204.73
储存:	冰箱保存
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Isotopic Labeled Analogues; Stimulant; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
参考文献	Melzacka, M., et al.: Pol. J. Pharmacol Pharm., 32, 551 (1980), Fong, M.H., et al.: J. Pharm. Pharmacol., 34, 674 (1982), Fiorella, D., et al.: Psychopharmacology, 119, 220 (1995), Maes, M., et al.: J. Clin. Psychopharmacol., 17, 358 (1997), Bo Wen, et al.: Drug Metab. Dispos., 36, 841 (2008),