产品编号：C378115

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C378115
名称:	(Z)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester
分子式:	C₂₃H₂₀ClNO₆
分子量:	441.86
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(Z)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester is an impurity in the synthesis of Amlodipine Besilate (A633500); a dihydropyridine calcium channel blocker which is also used as an antianginal and antihypertensive.
参考文献	Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996)