产品编号：C371580

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C371580
名称:	1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine
分子式:	C₁₈H₂₁ClN₂S
外观:	Beige Solid
分子量:	332.89
溶解度:	Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine is an intermediate in the synthesis of 3-Chloro-Vortioxetine which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
参考文献	Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)