产品编号：C371411

产品规格：100mg

产品价格：面议

---

产品详情

标准品编号:	C371411
名称:	2-Chloro-5-nitropyrimidin-4-ol
别名:	2-Chloro-5-nitro-4(3H)-pyrimidinone; 2-Chloro-5-nitro-4(1H)-pyrimidinone;
CAS号:	282101-98-8
分子式:	C₄H₂ClN₃O₃
分子量:	175.53
类别:	Building Blocks; Miscellaneous;
应用:	2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
参考文献	Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)