产品编号：C371065

产品规格：25g

产品价格：面议

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产品详情

标准品编号:	C371065
名称:	1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine Hydrochloride
别名:	4-(2-Azepan-1-ylethoxy)benzyl Chloride Hydrochloride
CAS号:	223251-25-0
参考CAS:	Free base: 212771-30-7
分子式:	C₁₅H₂₃Cl₂NO
分子量:	304.26
类别:	Building Blocks; Miscellaneous;
应用:	1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine Hydrochloride is a useful synthetic intermediate in the synthesis of Bazedoxifene (B129250); a nonsteroidal selective estrogen receptor modulator (SERM). Also used as an antiosteoporotic.
参考文献	Sathe, D.G., et al.: Indian Pat. Appl.ÂINÂ2011MU01317ÂAÂ20121207. Dec 7, 2012; van Hoorn, W., et al.: J. Med. Chem., 45, 584 (2002); Neubauer, B., et al.: Cancer Res., 63, 6056 (2003); Yan, X., et al.: Biochemistry, 43, 909 (2004)