产品编号：C368745

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	C368745
名称:	4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene
别名:	4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene; 4-Chloro-2-nitrophenyl 4-methoxyphenyl Ether
CAS号:	62966-77-2
分子式:	C₁₃H₁₀ClNO₄
分子量:	279.68
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene is used in the preparation of Amino Hydroxynimesulide (A618310), an analog of Nimesulide (N477500), an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
参考文献	Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998); Li, F. et al.: Chem. Res. Toxicol., 22, 72 (2009);