4-Chloro Kynurenine

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产品编号:C366940

产品规格:10mg

产品价格:面议


产品详情

标准品编号: C366940
名称: 4-Chloro Kynurenine
别名: α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; (+/-)-α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; 4-Cl-KYN; (+/-)-AV-101;
CAS号: 75802-84-5
分子式: C₁₀H₁₁ClN₂O₃
外观: Pale Yellow to Yellow Solid
熔点: >165°C (dec.)
分子量: 242.66
储存: 冰箱保存
溶解度: Aqueous Acid (Slightly), DMSO (Sparingly)
类别: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. ÂIts prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.
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