产品编号:C366940
产品规格:10mg
产品价格:面议
| 标准品编号: | C366940 |
| 名称: | 4-Chloro Kynurenine |
| 别名: | α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; (+/-)-α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid; 4-Cl-KYN; (+/-)-AV-101; |
| CAS号: | 75802-84-5 |
| 分子式: | C₁₀H₁₁ClN₂O₃ |
| 外观: | Pale Yellow to Yellow Solid |
| 熔点: | >165°C (dec.) |
| 分子量: | 242.66 |
| 储存: | 冰箱保存 |
| 溶解度: | Aqueous Acid (Slightly), DMSO (Sparingly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. ÂIts prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application. |
| 参考文献 | |