产品编号：C366605

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	C366605
名称:	(3S)-4-Chloro-3-hydroxybutyronitrile
别名:	(3S)-4-Chloro-3-hydroxybutanenitrile; (S)-4-Chloro-3-hydroxybutanenitrile; (S)-(-)-4-Chloro-3-hydroxybutyronitrile; (S)-4-Chloro-3-hydroxybutyronitrile;
CAS号:	127913-44-4
分子式:	C₄H₆ClNO
外观:	Clear Colourless Oil
分子量:	119.55
储存:	冰箱保存, under inert atmosphere
溶解度:	Chloroform (Sparingly), Methanol (Slightly)
类别:	Building Blocks; Miscellaneous;
应用:	(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
参考文献	Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);