产品编号：C360337

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C360337
名称:	5-Chloro-4-hydroxy-1,3-benzenedisulfonyl Dichloride
别名:	6-Chloro-1-phenol-2,4-disulfonyl Chloride;
参考CAS:	71293-22-6
分子式:	¹³C₆H₃Cl₃O₅S₂
分子量:	331.53
类别:	Standards; Isotopic Labeled Analogues;
应用:	5-Chloro-4-hydroxy-1,3-benzenedisulfonyl Dichloride is an intermediate used in the synthesis of Diclofenamide-13C6 (D436532), which is a labelled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
参考文献	Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);