产品编号：C292085

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C292085
名称:	CHIR 124
别名:	4-[((3S)-1-Azabicyclo[2.2.2]oct-3-yl)amino]-3-(1H-benzimidazol-2-yl)-6-chloroquinolin-2(1H)-one; 4-[(3S)-1-Azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro-2(1H)-quinolinone;
CAS号:	405168-58-3
分子式:	C₂₃H₂₂ClN₅O
分子量:	419.91
类别:	Research Tools;
应用:	CHIR 124 is a cell-permeable molecule with a quinolone-based structure. It inhibits checkpoint kinase 1 (Chk1) which regulates S and G2-M cekk cycle checkpoints in response to DNA damage. Application towards inhibition of tumor cell growth.
参考文献	Dufau, I. et al.: BMC Cancer, 12, 15 (2012); Tao, Y. et al.: Cell Cycle, 8, 1196 (2009);