Celastrol

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产品编号:C249500

产品规格:10mg

产品价格:面议


产品详情

标准品编号: C249500
名称: Celastrol
别名: 3-Hydroxy-2-oxo-24-nor-D:VIP(LA)friedooleana-1(10),3,5,7-tetraen-29-oic Acid; Tripterin; Tripterine (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid;
CAS号: 34157-83-0
分子式: C₂₉H₃₈O₄
外观: Orange Red Solid
熔点: 187-189°C
分子量: 450.61
储存: -20°C Freezer
溶解度: DMSO, Chloroform, Methanol
类别: Standards; Steroids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: An antioxidant natural product which inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies. Celastrol also has been shown to have the power to kill tumor cells and can work as an anticarcinogen. Celastrol is also a leptin sensitizer with the potential to reduce weight in obesity (see W499200).
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