CDDO Methyl Ester

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产品编号:C228100

产品规格:10mg

产品价格:面议


产品详情

标准品编号: C228100
名称: CDDO Methyl Ester
别名: 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402;
CAS号: 218600-53-4
分子式: C₃₂H₄₃NO₄
外观: 白色至Tan Solid
熔点: 215-223°C
分子量: 505.69
储存: 冰箱保存
溶解度: Chloroform (Slightly), Methanol (Slightly)
类别: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.
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