产品编号:C228100
产品规格:10mg
产品价格:面议
| 标准品编号: | C228100 |
| 名称: | CDDO Methyl Ester |
| 别名: | 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402; |
| CAS号: | 218600-53-4 |
| 分子式: | C₃₂H₄₃NO₄ |
| 外观: | 白色至Tan Solid |
| 熔点: | 215-223°C |
| 分子量: | 505.69 |
| 储存: | 冰箱保存 |
| 溶解度: | Chloroform (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer. |
| 参考文献 | |