产品编号：C227900
产品规格：250mg
产品价格：面议
| 标准品编号: | C227900 |
| 名称: | CCT036477 |
| 别名: | α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine; |
| CAS号: | 305372-78-5 |
| 分子式: | C₂₁H₁₈ClN₃ |
| 外观: | 灰白色至浅褐色固体 |
| 熔点: | >167°C (dec.) |
| 分子量: | 347.84 |
| 储存: | Amber Vial, 冰箱保存, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Ethyl Acetate (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes. |
| 参考文献 | |
