产品编号：C194705

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	C194705
名称:	(+)-Chloro(p-menth-3-yloxy)dimethylsilane
别名:	[1R-(1α,2β,5α)]-Chlorodimethyl[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]silane
CAS号:	19470-77-0
分子式:	C₁₂H₂₅ClOSi
外观:	Liquid
分子量:	248.86
类别:	Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
应用:	(+)-Chloro(p-menth-3-yloxy)dimethylsilane is a byproduct in the synthesis of Carfilzomib (2R,4R)-Diol (C183525), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);