产品编号：C178110

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C178110
名称:	6-(4-(1-Carboxyethyl)phenyl)-6-oxohexanoic Acid
别名:	2-[4-(1-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid
分子式:	C₁₅H₁₈O₅
分子量:	278.3
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	6-(4-(1-Carboxyethyl)phenyl)-6-oxohexanoic Acid is a possible metabolite of Loxoprofen (L472900, Na salt), a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
参考文献	Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001)