产品编号：C177308

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C177308
名称:	N,N'-Carbonylbis[L-glutamic acid]
别名:	Carglumic Acid Dimer
CAS号:	302941-52-2
分子式:	C₁₁H₁₆N₂O₉
分子量:	320.25
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N,N'-Carbonylbis[L-glutamic acid] is an impurity of the drug Carglumic Acid (C175965), which has been shown to have protective effects against ammonia intoxication and is used in the treatment of acute hyperammonemia. It has also been used to study the synthesis of urea-based inhibitors of glutamate carboxypeptidase II.
参考文献	Paik, W.K. et al.: Life Sci., 15, 1189 (1974); O'Connor, J.E. et al.: Eur. J. Pediat., 148, 540 (1989); Lee, J.H. et al.: Biochem. Biophys. Res. Chem., 248, 391 (1998); Kozikowski, A., et al.: J. Med. Chem., 47, 1729 (2004);