产品编号：C176130

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C176130
名称:	(E)-1-(4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5,7,7a-tetrahydro-1H-pyrazolo[3,4-c]pyridin-6(3aH)-yl)phenyl)-2-(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene Oxide
别名:	Axipaban Impurity;
分子式:	C₄₀H₃₆N₁₀O₇
分子量:	768.78
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(E)-1-(4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5,7,7a-tetrahydro-1H-pyrazolo[3,4-c]pyridin-6(3aH)-yl)phenyl)-2-(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene Oxide is an impurity of Apixaban (A726700) a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation
参考文献	Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);