产品编号：C175203

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	C175203
名称:	Canagliflozin Tetraacetate
别名:	(1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-Tetraacetate
CAS号:	866607-35-4
分子式:	C₃₂H₃₃FO₉S
外观:	白色固体
分子量:	612.66
储存:	冰箱保存
溶解度:	Chloroform, Ethyl Acetate, Methanol
类别:	Standards; Miscellaneous;
应用:	The title compound is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
参考文献	Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);