产品编号：C164685

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C164685
名称:	5-​[[[(2,​4-​Difluorophenyl)​methyl]​amino]​carbonyl]​-​1,​4-​dihydro-​3-​methoxy-​4-​oxo-​1-​(2-​oxoethyl)​-2-​pyridinecarboxylic Acid Methyl Ester
别名:	Methyl 5-((2,4-Difluorobenzyl)carbamoyl)-3-methoxy-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2-carboxylate
CAS号:	1646862-09-0
分子式:	C₁₈H₁₆F₂N₂O₆
外观:	Yellow Solid
分子量:	394.33
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Dichloromethane;
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	5-​[[[(2,​4-​Difluorophenyl)​methyl]​amino]​carbonyl]​-​1,​4-​dihydro-​3-​methoxy-​4-​oxo-​1-​(2-​oxoethyl)​-2-​pyridinecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Cabotegravir-d3 (C050102), which is the labelled form of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.
参考文献	Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)