Calcein AM (Mixture of Structural Isomers)

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产品编号:C125420

产品规格:1mg

产品价格:面议


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标准品编号: C125420
名称: Calcein AM (Mixture of Structural Isomers)
别名: N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy) methyl] Ester; Calcein Acetoxymethyl Ester; NSC 689290;
参考CAS: Component: 148504-34-1
分子式: C₄₆H₄₆N₂O₂₃
分子量: 994.86
类别: Research Tools; Molecular Biology; Fluorescent Reagents; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
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