产品编号：C051600
产品规格：5mg
产品价格：面议
| 标准品编号: | C051600 |
| 名称: | Cabozantinib N-oxide |
| 别名: | N-[4-[(6,7-Dimethoxy-1-oxido-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| CAS号: | 1621681-63-7 |
| 分子式: | C₂₈H₂₄FN₃O₆ |
| 外观: | 白色至白色固体 |
| 熔点: | 143 - 147°C |
| 分子量: | 517.51 |
| 储存: | Hygroscopic, 冰箱保存, under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Cabozantinib N-oxide is a impurity of Cabozantinib (X745500), a medication used to treat medullary thyroid cancer. As well, it can be used in biological study. Computational network biological approach based on pathway cross-talk inhibition identified new synergistic drug combinations using raloxifene and cabozantinib for treatment of human breast cancer in xenograft mouse model. Potent c-MET inhibitor. |
| 参考文献 | |
