产品编号：C051502

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C051502
名称:	Cabozantinib-d4 L-Malate Salt
别名:	N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide-d4 (2S)-2-Hydroxybutanedioic Acid; Cabozantini-d4 S-Malate; XL 184-d4;
参考CAS:	未标记：1140909-48-3
分子式:	C₃₂H₂₆D₄FN₃O₁₀
分子量:	639.62
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Cabozantinib-d4 L-Malate Salt, is the labeled analogue of Cabozantinib L-Malate Salt (C051500), which is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and has been shown to reduce tumor growth, metastasis, and angiogenesis.
参考文献	Camp, R., et al.: Cancer, 86, 2259 (1999), Morello, S., et al.: J. Cell Physiol., 189, 285 (2001), Zhang, Y., et al.: Oncogene, 21, 217 (2002), Wells, S., et al.: J. Clin. Oncol., 28, 767 (2010),