产品编号：B942848

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	B942848
名称:	3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4-(dimethylamino)butanoyl)benzonitrile
分子式:	C₂₀H₃₂N₂O₂Si
分子量:	360.57
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4-(dimethylamino)butanoyl)benzonitrile is an intermediate in the synthesis of 4-[4-(Dimethylamino)-1-oxobutyl]-3-(hydroxymethyl)benzonitrile (D461745). 4-[4-(Dimethylamino)-1-oxobutyl]-3-(hydroxymethyl)benzonitrile is a by-product in the synthesis of Citalopram/Escitalopram, a selective serotonin reuptake inhibitor that relieves the symptoms of diabetes and is used in the treatment of depression.
参考文献	Andersen, G., et al.: Stroke, 25, 1099 (1994); Sindrup, S., et al.: Clin. Pharmacol. Ther., 52, 547 (1992); Vedantham, R.,e t al.: Org Process Res. Dev., 17, 798 (2013)