产品编号：B942758

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B942758
名称:	4-((tert-Butyldimethylsilyl)oxy)-2,5-bis(trifluoromethyl)aniline
分子式:	C₁₄H₁₉F₆NOSi
外观:	Dark Orange Liquid
分子量:	359.38
储存:	-20°C Freezer, Under inert atmosphere
溶解度:	Dichloromethane
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-((tert-Butyldimethylsilyl)oxy)-2,5-bis(trifluoromethyl)aniline is an intermediate in the synthesis of 4’-Hydroxy Dutasteride (H825530), which is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
参考文献	Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)