产品编号：B942753

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	B942753
名称:	(4S,5R)-5-((S)-3-((tert-Butyldimethylsilyl)oxy)-3-(4-fluorophenyl)propyl)-4-(4-((tert-butyldimethylsilyl)oxy)phenyl)-3-(4-fluorophenyl)-1,3-oxazinan-2-one
分子式:	C₃₇H₅₁F₂NO₄Si₂
外观:	Clear Oil
分子量:	667.97
溶解度:	Dichloromethane, Ethyl Acetate
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(4S,5R)-5-((S)-3-((tert-Butyldimethylsilyl)oxy)-3-(4-fluorophenyl)propyl)-4-(4-((tert-butyldimethylsilyl)oxy)phenyl)-3-(4-fluorophenyl)-1,3-oxazinan-2-one is an intermediate in the synthesis of 4’-O-Benzyloxy Ezetimibe Diol Impurity (B287130). 4’-O-Benzyloxy Ezetimibe Diol Impurity is an impurity of Ezetimibe (E975000); an antihyperlipoproteinemic and cholesterol absorption inhibitor.
参考文献	Gajjar, A.K., et al.: Open Conf. Proc. J., 2, 108 (2011); van Heek, M., et al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., et al.: Brit. J. Pharmacol., 129, 1748 (2000)