产品编号：B820030

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	B820030
名称:	O-t-Butyldiphenylsilylhydroxylamine
别名:	O-[(1,1-Dimethylethyl)diphenylsilyl]hydroxylamine; (t-Butyldiphenylsilyloxy)amine; O-[(1,1-Dimethylethyl)diphenylsilyl]-hydroxylamine; O-DPTBS hydroxylamine
CAS号:	103587-51-5
分子式:	C₁₆H₂₁NOSi
外观:	白色固体
熔点:	82 - 85°C
分子量:	271.43
溶解度:	Chloroform, Ethyl Acetate (Slightly)
类别:	Standards; Miscellaneous;
应用:	O-t-Butyldiphenylsilylhydroxylamine is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
参考文献	Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H.K., et al.: Drug Metab. Dispos., 39, 2264 (2011);