产品编号：B809235

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	B809235
名称:	tert-Butyl 2-((4R,6R)-6-(2-(2-(3-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
分子式:	C₄₀H₄₇FN₂O₅
外观:	Yellow Solid Foam
分子量:	654.81
储存:	Room Temperature
溶解度:	Chloroform, Dichloromethane, Dimethylsulfoxide, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	tert-Butyl 2-((4R,6R)-6-(2-(2-(3-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is an intermediate in the synthesis of 3-Fluoro Atorvastatin Sodium Salt (F587915). 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
参考文献	Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)