产品编号：B809210

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B809210
名称:	tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
别名:	N-[(1S)-3-Methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]carbamic Acid 1,1-Dimethylethyl Ester; [(1S)-3-Methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]carbamic Acid 1,1-Dimethylethyl Ester; (2R)-2-[(2S)-2-(tert-Butoxycarbonylamino)-4-methylpentanoyl]-2-methyloxirane
CAS号:	247068-82-2
参考CAS:	Deleted:1334608-29-5
分子式:	C₁₄H₂₅NO₄
分子量:	271.35
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Wang, P., et al.: Process for preparation of carfilzomib, China Patent 2015010436, Jan 29, 2015; Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)