产品编号：B696605

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B696605
名称:	6-​Bromo-​7-​methoxy-​1,​1-​dimethyl-​3,​4-​dihydronaphthalen-​2(1H)​-​one
别名:	6-Bromo-3,4-dihydro-7-methoxy-1,1-dimethyl-2(1H)-naphthalenone;
CAS号:	1256578-99-0
分子式:	C₁₃H₁₅BrO₂
分子量:	283.16
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	6-​Bromo-​7-​methoxy-​1,​1-​dimethyl-​3,​4-​dihydronaphthalen-​2(1H)​-​one is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Kinoshita, K. et al.: J. Med. Chem., 64, 6286 (2011); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);