产品编号：B695585

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B695585
名称:	BMS 309403
别名:	2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]-acetic acid
CAS号:	300657-03-8
分子式:	C₃₁H₂₆N₂O₃
分子量:	474.55
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	FABP4 Inhibitor is a cell-permeable biphenylazolo-oxyacetate that acts as a potent and selective inhibitor of VIP(LA)FABP (adipocyte Fatty-Acid-Binding Protein) by targeting its fatty acid-binding pocket (Ki = < 2 nM in a competitive binding assay using 1,8-ANS), while exhibiting much lower affinity for muscle and epidermal FABP's (Ki = 250 nM and 350 nM, respectively).
参考文献	Lan, H., et al: Journal of Lipid Research 52(4), 646-656 (2011); Sulsky, R. et al.: Bioorganic & Medicinal Chemistry Letters 17(12), 3511-3515 (2007).