产品编号：B694060

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	B694060
名称:	1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine
别名:	4-Amino-3,3-difluoro-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; tert-Butyl 4-Amino-3,3-difluoropiperidine-1-carboxylate
CAS号:	1255666-48-8
分子式:	C₁₀H₁₈F₂N₂O₂
分子量:	236.26
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine is synthetic building block for pharmaceuticals. It can be obtained from N-Benzyl-β-alanine Ethyl Ester (B232975) which is used as a reagent in organic synthesis including that of dipivaloyloxyphenyl aminopropionate β-agonist prodrugs which are used in the treatment of psoriasis. N-Benzyl-β-alanine Ethyl Ester (B232975) is also used in the synthesis of N,N'-dithiobis(N-benzyl-β-alanine) dethyl ester, which is an important intermediate of insecticide OK-135, and in synthesis of spiropiperidine-based orexin-2 receptor (OX2R) antagonists.
参考文献	Gill, H., et al.: Eur. J. Med. Chem., 31, 847 (1996); Huang, M., et al.: Hunan Huagong, 30, 13 (2000); Fujimoto, T., et al.: Bioorg. Med. Chem. Lett., 21, 6409 (2011);