产品编号：B693900

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	B693900
名称:	tert-Butylsulfinamide
别名:	(±)-tert-Butylsulfinamide; 1,1-Dimethylethylsulfinamide; 2-Methyl-2-propanesulfinamide; 2-Methylpropan-2-sulfinamide; tert-Butylsulfinamide; 2-Methyl-2-propanesulfinamide
CAS号:	146374-27-8
分子式:	C₄H₁₁NOS
外观:	白色至淡黄色固体
熔点:	102-105°C
分子量:	121.2
储存:	冰箱保存
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Building Blocks; Miscellaneous;
应用:	tert-Butylsulfinamide can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. tert-Butylsulfinamide is also used as a reagent in the synthetic preparation of amide series as BACE1 inhibitor and potential anti-Alzheimer’s drug.
参考文献	Szallasi, A., et al.: Pharmacol. Rev., 51, 159 (1999), Montell, C., et al.: Mol. Cell., 9, 229 (2002), Ryu, C., et al.: Bioorg. Med. Chem. Lett., 14, 1751 (2004), Suh, Y., et al.: J. Med. Chem., 48, 5823 (2005); Woltering, T. J., et al.: Bioorg. Med. Chem. Lett., 23, 4239 (2013)