产品编号：B693180

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B693180
名称:	42-O-tert-Butyldimethylsilyl Rapamycin
分子式:	C₅₇H₉₃NO₁₃Si
外观:	White Foamy Solid
分子量:	1028.43
溶解度:	Chloroform, Methanol
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	42-O-tert-Butyldimethylsilyl Rapamycin is an intermediate in the synthesis of 28-Ethylhydroxy Rapamycin (E678640), which is an impurity of Everolimus (E945400),a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
参考文献	Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)