产品编号：B693175

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	B693175
名称:	2-((tert-Butyldimethylsilyl)oxy)ethyl 2,2,2-trichloroacetimidate
分子式:	C₁₀H₂₀Cl₃NO₂Si
外观:	Colourless Oil
分子量:	320.72
溶解度:	Chloroform, Methanol
类别:	Building Blocks; Miscellaneous;
应用:	2-((tert-Butyldimethylsilyl)oxy)ethyl 2,2,2-trichloroacetimidate is an intermediate in the synthesis of 28-Ethylhydroxy Rapamycin (E678640), which is an impurity of Everolimus (E945400),a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
参考文献	Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)