O-tert-Butyl-dimethylsilyl Curcumin

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产品编号:B691020

产品规格:1g

产品价格:面议


产品详情

标准品编号: B691020
名称: O-tert-Butyl-dimethylsilyl Curcumin
别名: (1E,4Z,6E)-7-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one
CAS号: 911292-36-9
分子式: C₂₇H₃₄O₆Si
外观: Yellow Solid
熔点: >129°C (dec.)
分子量: 482.64
储存: Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
类别: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
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