产品编号：B682500
产品规格：10mg
产品价格：面议
| 标准品编号: | B682500 |
| 名称: | Bromoconduritol (Mixture of Isomers) |
| 别名: | 6-Bromo-3,4,5-trihydroxy Cyclohex-1-ene; 6-Bromo-4-cyclohexene-1,2,3-triol; |
| CAS号: | 42014-74-4 |
| 分子式: | C₆H₉O₃Br |
| 外观: | 白色至白色固体 |
| 熔点: | 115-118°C |
| 分子量: | 209.04 |
| 溶解度: | Water |
| 类别: | Standards; Enzyme Activators and Inhibitors; Glycosidase Inhibitors; |
| 应用: | Bromoconduritol selectively inhibits mammalian alpha-glucosidase 2 (Glc2/Glc1 glucosidase in the glycoprotein processing pathway), yeast alpha-glucosidase, and some beta-glucosidases. It does not inhibit mammalian alpha-glucosidase 1 (Glc3-glucosidase) or mammalian Golgi mannosidase 1 (alpha-1,2-specific) in the glycoprotein processing pathway; the formation of lipid-linked oligosaccharide precursor (dolichol pyrphosphate oligosaccharide) and the transfer of lipid-linked oligosaccharide to proteins. Preparations in ice-cold H2O should be used immediately. The half-time for decomposition of bromoconduritol A (debromination) is 16 min (H2O, pH 7.3, 37oC). Under similar conditions, the half-life of bromoconduritol B is 2 mins. Working concentration for the inhibition of glycoprotein processi |
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