产品编号：B676683
产品规格：2.5mg
产品价格：面议
| 标准品编号: | B676683 |
| 名称: | 4BP-TQS |
| 别名: | 4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide |
| CAS号: | 360791-49-7 |
| 分子式: | C₁₈H₁₇BrN₂O₂S |
| 外观: | Pale Brown Solid |
| 熔点: | >202°C (dec.) |
| 分子量: | 405.31 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 4BP-TQS is an agonist of human α7 nicotinic acetylcholine receptor (a7-nAChR), activates the channel via binding to an allosteric transmembrane site. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC10 concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone. |
| 参考文献 | |
