产品编号：B675390

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	B675390
名称:	Borrelidin
别名:	(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-Cyclopentanecarboxylic Acid; [2S-[2R*(1S*,2S*),4E,6Z,8S*,9R*,11S*,13R*,15R*,16R*]]-2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)cyclopentanecarboxylic Acid; Oxacyclooctadecane Cyclopentanecarboxylic Acid deriv.; (-)-Borrelidin; Borrelidine; NSC 216128; Treponemycin
CAS号:	7184-60-3
分子式:	C₂₈H₄₃NO₆
分子量:	489.64
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Borrelidin is a nitrile containing polyketide acting as a potent inhibitor of bacterial and eukaryotic threonyl-tRNA synthases. Used to interrupt protein translation in the synthesis of new antimalarial agents due to the rise of resistance to already existing medications.
参考文献	Schulze, C. et al.: J. Nat. Prod., 77, 2570 (2014); Novoa, E. et al.: Proc. Nat. Acad. Sci. United St. Amer., 111, E5508 (2014);