产品编号：B596315

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	B596315
名称:	BMS 754807
别名:	(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide
CAS号:	1001350-96-4
分子式:	C₂₃H₂₄FN₉O
分子量:	461.49
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	BMS 754807 is an inhibitor of insulin-like growth factor 1 receptor (IGF-1R) . It inhibits cell proliferation or induces apoptosis in a variety of cancer cells in vitro. It also inhibits the growth of tumor xenografts in mice. Potent IGF-1R inhibitor.
参考文献	Carboni, J., et al.: Mol. Cancer Ther., 8, 3341 (2009); Awasthi, N., et al.: Mol. Cancer Ther., 11, 2644 (2012); Dayyani, F., et al.: PLoS One, 7, 1 (2012)