产品编号：B596090

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	B596090
名称:	BMS-345541 Trifluoroacetic Acid Salt (1:2)
别名:	N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine Trifluoroacetic Acid Salt;
参考CAS:	Free Base: 445430-58-0
分子式:	C₁₄H₁₇N₅ • 2(C ₂HF₃O₂)
分子量:	255.322114
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	BMS-345541 Trifluoroacetic Acid Salt is a potent, selective, and allosteric site-binding inhibitor of IKK β (IKK-2) and shows 10 times greater selectivity over IKK α (IKK-1). BMS-345541 also inhibits cellular Iκβα phosphorylation and has some anti-inflammatory properties.
参考文献	Baxter, A., et al.: Bioorg. Med. Chem. Lett., 14, 2817 (2004); Kishore, N., et al.: J. Biol. Chem., 278, 32861 (2003)