产品编号：B592500
产品规格：5mg
产品价格：面议
| 标准品编号: | B592500 |
| 名称: | (S)-(-)-Blebbistatin |
| 别名: | (3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one; (-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one; (-)-Blebbistatin; |
| CAS号: | 856925-71-8 |
| 分子式: | C₁₈H₁₆N₂O₂ |
| 外观: | Bright Yellow Solid |
| 熔点: | >205°C (dec.) |
| 分子量: | 292.33 |
| 储存: | -20°C Freezer |
| 溶解度: | Chloroform, Dichloromethane, DMSO, Ethyl Acetate, Methanol |
| 类别: | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis at 50-100µM. [Blebbistatin:a]D= -103 (c= 1.21 CHCl3) (-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one Blebbistatin is a selective inhibitor of nonmuscle myosin II; Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells. |
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