产品编号：B488282

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B488282
名称:	2-Methyl-2-[(trimethylsilyl)oxy]propanenitrile-d6
CAS号:	107090-98-2
参考CAS:	18296-11-2
分子式:	C₇H₉D₆NOSi
外观:	Liquid
分子量:	163.32
类别:	Building Blocks; Isotopic Labeled Analogues; Miscellaneous;
应用:	2-Methyl-2-[(trimethylsilyl)oxy]propanenitrile-d6 is an intermediate for the synthesis of O-Desethyl Resiquimod-d6 (D228577), which is the labelled analogue of O-Desethyl Resiquimod (D228575), which is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
文献	Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);