产品编号：B448532
产品规格：2.5mg
产品价格：面议
| 标准品编号: | B448532 |
| 名称: | Bisindolylmaleimide XI Hydrochloride-d6 |
| 别名: | 3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Hydrochloride-d6; Ro 31-0432-d6 |
| 参考CAS: | 未标记：145333-02-4 |
| 分子式: | C₂₈H₂₃D₆ClN₄O₂ |
| 分子量: | 495.05 |
| 类别: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Bisindolylmaleimide XI Hydrochloride-d6 is the isotope labelled analog of Bisindolylmaleimide XI Hydrochloride (B448530); a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCα by Bisindolylmaleimide XI and other similar PKC inhibitors has been associated with enhanced cardiac contractility and protection from heart failure. Bisindolylmaleimide XI has been shown to prevent T-cell activation and proliferation associated with chronic inflammatory responses in vivo. |
| 文献 | |
