产品编号：B441215

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	B441215
名称:	(S)-2-((2S,5S,8S,11S)-5-Benzyl-8-isobutyl-14-morpholino-4,7,10,13-tetraoxo-2,11-diphenethyl-3,6,9,12-tetraazatetradecanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide
分子式:	C₆₅H₈₈N₈O₁₀
分子量:	1141.44
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-2-((2S,5S,8S,11S)-5-Benzyl-8-isobutyl-14-morpholino-4,7,10,13-tetraoxo-2,11-diphenethyl-3,6,9,12-tetraazatetradecanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide is an impurity of Carfilzomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);