产品编号：B431655

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B431655
名称:	1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea
分子式:	C₂₅H₁₄Cl₂F₄N₂O
分子量:	505.29
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea is an impurity of Sorafenib (S676850) which is a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),