产品编号：B426465

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	B426465
名称:	2,6-Bis(methoxymethyl)aniline
分子式:	C₁₀H₁₅NO₂
外观：	Light Yellow Oil
分子量:	181.23
溶解度:	Dichloromethane, Ethyl Acetate, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2,6-Bis(methoxymethyl)aniline is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
文献	Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001); Griffin, D. et al.: J. Am. Chem. Soc., 134, 13103 (2012);