产品编号：B412963

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B412963
名称:	1,5-Bis([1,1'-biphenyl]-4-yl(phenyl)methyl)-1H-imidazole
分子式:	C₄₁H₃₂N₂
分子量:	552.71
溶解度:	Dichloromethane, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1,5-Bis([1,1'-biphenyl]-4-yl(phenyl)methyl)-1H-imidazoleis an impurity in the synthesis of 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole which is derived from 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (B397925), which is a structural isomer of Bifonazole (B383400) that is an anti-fungal agent used in the treatment of skin diseases. Bifonazole causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.
文献	Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);