产品编号：B399700

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B399700
名称:	BIRH 414
别名:	11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one; BIRH 414 BS; USP Nevirapine Related Compound A; Nevirapine EP Impurity A; Nevirapine USP Related Compound A
杂质:	Nevirapine EP Impurity A; Nevirapine USP Related Compound A
CAS号:	133627-17-5
分子式:	C₁₄H₁₄N₄O
分子量:	254.29
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	BIRH 414 (Nevirapine EP Impurity A; Nevirapine USP Related Compound A) is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).
文献	Tavlarakis, A., et al.: Molec. Stimu., 35, 1224 (2009); Singh, J., et al.: Oxidation. Commun., 32, 13 (2009); Rizzo, R.C., et al.: J. Med. Chem., 45, 2970 (2002);