产品编号：B384500

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B384500
名称:	BIIB 021
别名:	6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine; 6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-yl]amine;
CAS号:	848695-25-0
分子式:	C₁₄H₁₅ClN₆O
分子量:	318.76
类别:	Research Tools;
应用:	BIIB 021 an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90. Studies show that BIIB 021 adminisitration led to degradation of Hsp90 client proteins measured in tumor tissue and resulted in the inhibition of tumor growth in several human tumor xenograft models.
文献	Lundgren, K. et al.: Mol. Cancer Ther., 8, 921 (2009); Boell, B. et al.: Clin. Cancer Res., 15, 5108 (2009); Yin, X. et al.: Int. J. Cancer, 126, 1216 (2010);